![]() ![]() These studies indicate that Shingrix prevented 68% and 87% of cases, respectively. In the first study, involving people who had received an autologous (from the patient’s own body) stem cell transplant, the number of people who had herpes zoster was 49 (out of 870) in the Shingrix group compared with 135 (out of 851) in the placebo group in the second study, involving patients with blood cancer, these figures were 2 (out of 259 people) and 14 (out of 256), respectively. Shingrix was also effective in two studies in adults aged 18 years and above at increased risk of developing herpes zoster. This indicates that Shingrix prevented 91% of shingles cases and 89% of cases of post-herpetic neuralgia in adults aged 70 years and older. ![]() After 4 years, 4 adults had had post-herpetic neuralgia in the Shingrix group compared with 36 in the placebo group. Looking at the results for adults in this age group from both studies together, 25 adults out of 8,250 who received Shingrix had shingles within 4 years after vaccination compared with 284 out of 8,346 who received placebo. The second study involved adults aged 70 and over who received either Shingrix or placebo. Side effects can last two or three days, and. This indicates that Shingrix prevented 97% of shingles cases and 100% of cases of post-herpetic neuralgia in this study. Skin rash, joint pain, flu-like symptoms, headaches and fatigue are some complaints from patients whove had the recently approved Shingrix vaccine. After almost 4 years, nobody had had post-herpetic neuralgia in the Shingrix group compared with 18 in the placebo group. After just over 3 years on average, 6 adults had had shingles in the Shingrix group compared with 210 in the placebo group. In the first study, 7,695 received Shingrix and 7,710 received placebo (a dummy treatment). Shingrix has been shown in two main studies to be effective at preventing shingles and post-herpetic neuralgia in patients 50 years and older.
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